ʻO ke aʻoʻana i ka SnowTull

I kēia manawa, jama itcology (inā 33.012) i paʻiʻia i keʻano he nui o ka lāʻau lapaʻau o ka lāʻau lapaʻau. Tumor dna mybylation a me ka stratification stratification) ". ʻO kēia noiʻiʻo ia ka haʻawina multicenter mua ma ka honua e pili ana i keʻano o keʻano o ka cyctical canith canice . ^. Ua loiloi nuiʻia ka hoʻomaikaʻiʻana e ka'ōlelo Hawaiʻi a me kāna hoʻoponopono, a ua inoaʻiaʻo ia he pepa hōʻike i loko o kēia pilikia maiʻAmelika Hui PūʻIa e nānā iā ia. Ua hōʻikeʻia nō hoʻi ka noiʻi e ka genomeweb, he alakaʻi alakaʻi alakaʻi iʻAmelika Hui PūʻIa.

ʻO ka corcer colordel (crc) he mea kolohe maʻamau maʻamau o ka gestrointentinal stestrointentinal ma china. 2020ʻAmelikaʻAmelika no ka noiʻiʻana ma ka maʻi maʻi (IRCC) e hōʻike ana i nā kūlana o Kina; 286,000 Dead account account no 1/3 o ka honua, ka paeʻana o ka honua,ʻo ia ka hopena o ka hopena o ka makeʻana o Cancer ma Kina. Ka hapalima o ke kumu o ka make ma Kina. He mea pono ia ma waena o nā mea maʻi i hōʻikeʻia, nā mea hana TMM, II, II.6%, 30.7% a me 8. ʻOi aku ma mua o 80% o nā mea maʻi i waena o nā mea i waena a me ka nui o nā hanana a me nā mea ola a me nā mea ola maikaʻiʻole. E like me nā helu helu o ke kikowaena ceran cerance o ke aupuni ʻO nā maʻi maʻi maʻi maʻi e hōʻeha ana i ka maʻi a ma lalo o ka nui o ka hoʻokele waiwai [2].
Hiki ke neʻeʻia ka nui o ka hapa o nā molī colord i hōʻemiʻia, a uaʻikeʻia ka nui o ka tumor,ʻoi aku ka kiʻekiʻe o ka nui o ka piʻiʻana o ka nui o ka nui o ka radical. ʻO nā kumukūʻai elima mau makahiki elima mau makahiki o ka corcer colcer ma ka heluna he 90.1%, 72%, ii, II, IIWE, MAE MA IV.
ʻO ka maʻi maʻi liʻiliʻi (MRD) kahi kumu nui o ka tumor recurrence ma hope o ka mālamaʻana. I nā makahiki i hala iho nei,ʻo MRD ENDING TUSPORT E LOAʻI E PILI ANA I KA LOHE ANA I KA LAHUI ANA O KA LAHUI ANA O KA LAHUI E PILI ANA ʻO ka ho'āʻoʻanaʻo CTDNAʻo CTDNAʻO ka pono o ke liloʻana, maʻalahi, wikiwiki, me ka wikiwiki o Heterogeneity.
ʻO nā alakaʻi NCCN US no ka COLOCE CANCE a me nā alakaʻi CORD COCO no nā mea maʻi Calcoment Eia nō naʻe,ʻoi aku ka nui o nā haʻawina e pili ana i nāʻenehana ctdna i hoʻokumuʻia ma luna o kaʻenehana kiʻekiʻe (NGS)
I ka hihia o ka SECE II SOREMO COCERS CANCE CANCERS, NGS-ENDNA DYMNA DYNACICH TO $ 10,000 no kahi kipa hoʻokahi a hiki i nā manawaʻelua a hiki iʻelua mau pule. Me ka hōʻike Multimine mithylation i kēia noiʻi, calliquaq®, hiki i nā mea maʻi ke nānā i kahi hapa o ka uku.
Wahi a nā hihia 560,000 mau hihia hou o ka cancer colorfal i kēlā me kēia makahiki, a laila e pili ana i ka mākeke o MRD i nā makahiki he nui.
Hiki keʻikeʻia e loaʻa nā hopena noiʻi he nui a koʻikoʻi. Ma o nā kula ulu nui nui, ua hōʻoia ia e pili ana i keʻano o ke koko ctdna Hoʻokumuʻia ke aʻoʻana ma luna o ColoniQ®, kahi hōʻikeʻo Multi-GeneLu-General Cancer no ka huiʻana a me keʻano o ka noiʻana i keʻano o ke kiʻiʻana ma keʻano o keʻano.
GastroentEroly (If33.88) ʻO ka maʻi maʻi o ke kanesal, aʻo ka mua iʻimi mua i ka hanaʻana i ka palapala noi ma ka nānāʻana o ka prognosis

E hōʻoia hou i ka noiʻana o ka CTDNA i ka cratratication i ka hopena o keʻano he nui o keʻano o keʻano he nui. adjuvant Therapy no ka hoʻokūkū koko ctdna.
Mua, uaʻikeʻiaʻo ia ka ho'āʻoʻana e hiki ke wānana i ka hopena o ka hoʻomaikaʻiʻana i nā maʻi maʻi cheursent Loaʻa i nā mea maʻi CTDNAET CTDNA-maikaʻi i loaʻa i kahi kiʻekiʻe o ka postoperative recurrence ma mua o nā mea maʻi ctdna-maikaʻi (22.0%> 4.7%> 4.7%). ʻO ka hopena mua mua CTDNAATIVE CTDNA i wānana i ka hopena paʻakikī: hoʻokahi mahina ma hope o ka mea e koiʻia ai nā mea maʻi ctdna-maikaʻi Loaʻa ka hui pū kekahi i hui pūʻiaʻo CTDNA a me CAE i ka hana maikaʻiʻana i ka hanaʻana (AUC = 0.839).
ʻO keʻano o ka hoʻouluʻiaʻana me nā meaʻoi aku ka nui o nā mea koʻikoʻi no ka pilikia o nā maʻi maʻi maʻi. E pili ana i kēia,ʻo nā mea maʻi i hoʻonohonohoʻia me ka papa hana hana i nā cubground likeʻole (T4 / N2) a me ka haʻahaʻa)). Ua loaʻa ka loiloi i nā mea maʻi ma ka subgroup kiʻekiʻe o CTDNA-maikaʻi i loaʻa i kahi helu haʻahaʻa haʻahaʻa I ka palena haʻahaʻa haʻahaʻa o nā mea maʻi o CTDNA-maikaʻi,ʻaʻoheʻano koʻikoʻi ma waena o nā kiʻi kiʻi maikaʻi a me nā hopena maikaʻiʻole; ʻOiaiʻo CTDNA-maikaʻi nā mea maʻi maikaʻi loa i loaʻa i ka prognosis maikaʻi loa ma mua o nā mea maʻi ctdna-maikaʻi a me kahi manawa hou hou (RF ʻO ka hana a me ka haʻahaʻa haʻahaʻa haʻahaʻa II Viareptal Cancer āpau āpau i nā maʻi CTDNA-maikaʻiʻole i loko o nā makahikiʻelua; No laila,ʻo ka hoʻohuiʻana o ka ctdna me nā hiʻohiʻona lapaʻau e manaʻoʻia e hoʻonui hou i ka stratification stratification aʻoi aku ka wānana hou.

Kiʻi 1.ʻO Plasma Ctdna Ctdna ma Pom1 no kaʻike muaʻana o ke kaʻa kaʻa colorfal corurrence
ʻO nā hopena hou aʻe o ka ho'āʻoʻana e hōʻike ana i ka loiloi o ka recurrence me ka hōʻikeʻana i ka maʻi ma mua o ka loaʻaʻana o nā maʻi hiki keʻike mua i ka loaʻaʻana o ka maʻi refurrence a me ka manawa manawa.

Kiʻi 2.ʻO Ctdna i hōʻikeʻia e pili ana i nā cohortinal ma keʻano he lōʻihi lōʻihi eʻike ai i ka corurcel corcurence

"He helu nui o nā haʻawina lāʻau lapaʻau e alakaʻi i keʻano o keʻano o keʻano o ka hōʻoiaʻana o ka cratralfence

ʻO ka maikaʻi o ke kohoʻana iā DNA MNITYLATION e like me ka mea kākau moʻolelo ma luna o kaʻikeʻana o GENETING,ʻaʻole pono e pale i nāʻano hana maʻamau
ʻO kēia noiʻi a me nā haʻawina e pili ana i nā hōʻikeʻo CTDNA-e pili ana i ka maʻi o ka CORCETERENCE FORCECE no ka hoʻomaikaʻiʻana i keʻano o keʻano o keʻano o keʻano
ʻO ka mahina o MRD ka wikiwiki e holo wikiwiki nei me kahi helu o ka mea makemakeʻole, nā mea waiwai nui a me nā fenomic a me nā fenom. Manaʻo mākou e hoʻomau ka callotaq® e hoʻonohonoho i nā haʻawina nui nui a hiki ke lilo i mea hou o ka hoʻokolohua loea.
Nā manaʻo aʻoaʻo
[1] 'WElelo L, L, Wang D, Zoo Fat, Xu Said Credition. JAMA OCCOL. 2023 Apr 20.
[2] "ʻO ke kaumaha o nā maʻi maʻi maʻi colordel i ka lehulehu Kina: ua loli ia i nā makahiki i hala? , Belwers Pukana ChhinamIlogy, vl. 41, no. 10, Okatoba 2020.
3 13ʻO ka tarazona n, gimeno-Vastonde F, Gambardella V, et al. Kuhiʻia e ka mea e hiki mai ana ma hope o ka squulating scout-tumor dna no ka nānāʻana i ka maʻi kino kino i loko o ka maʻi color color. Ann oncol. Nov 1, 2019; 30 (11): 1804-1812.
[4] Taiieb J, André T, Aclin E. E hoʻomaikaʻi i ka hana maʻi non-metastatic, a me nā hiʻohiʻona hou. Ua mālamaʻo Cancer iā Rev. 2019; 75: 1-11.